Sphingosylphosphorylcholine is upregulated in the stratum corneum of patients with atopic dermatitis
To clarify the functional relevance of sphingomyelin (100) deacylase to the ceramide deficiency seen in atopic dermatitis (AD), we developed a new highly sensitive method and measured the metabolic intermediate sphingosylphosphorylcholine (copyright) that accumulates in the stratum corneum.copyright in intercellular lipids extracted from stratum co